| abstract |
Compounds represented by formula (I) or formula (II) having a function of inhibiting the release of TNFα, and salts or hydrates that can be used in the pharmacology thereof, and methods and applications thereof, wherein A and B are each CH 2 represents CO, SO, SO 2 , D represents S, NH, NC 1-6 alkyl group, R 1 represents H, 1-2 equivalent or different F, C1, Br, C 1-4 alkyl, OH, OC 1-4 alkyl, NO 2 , NHC (O) C 1-4 alkyl, NH 2 , NH (C 1-4 alkyl), N (C 1-4 alkyl) 2 . |