| abstract |
The invention relates to 3- (3-amino-2- (R) -hydroxypropyl) -1- (4-fluorophenyl) -8- (8-methylnaphthalen-1-ylmethyl) -1,3,8 Salts of triaza-spiro [4.5] decan-4-one, pharmaceutical compositions comprising them and their use in treating disorders and conditions controlled by NOP, such as depression, anxiety, alcohol abuse, etc. It is about. The invention also relates to 3- (3-amino-2- (R) -hydroxypropyl) -1- (4-fluorophenyl) -8- (8-methylnaphthalen-1-ylmethyl) -1,3, It relates to a process for the preparation of 8-triaza-spiro [4.5] decan-4-one and its corresponding salts. |