http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20090070755-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_717c792fca7cc9c290c9db33e8fe078b |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82B3-0038 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5123 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-513 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82B3-00 |
filingDate | 2007-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f9f2e5df94cb1381b4416c6d1f9a365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70866955e153a1937a25eaab8db05dc4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ef69874929b9248999c1f2984b46f1c |
publicationDate | 2009-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20090070755-A |
titleOfInvention | Supercritical Nanostructure Manufacturing Method Containing Triclosan Applying Density Fluctuation Theory |
abstract | The present invention relates to a method for producing a supercritical nanostructure of triclosan, a drug using a supercritical fluid process applying molecular association theory due to density fluctuations near the critical point, and a mixture in which the drug triclosan and a biodegradable polymer are dissolved in an organic solvent. Supercritical fluid, comprising spraying the solution with a supercritical fluid to contact the particles to produce triclosan and biodegradable polymer structure particles, and introducing the supercritical fluid to the particles to remove the organic solvent used in the mixed solution. It relates to a method for producing a supercritical nanostructure of a novel drug using the process. Triclosan, a drug substance that has not been tried until now, was used, and a poly-isopropyl-butyl poly-isopropyl-butylmethacrylate-acrylic acid copolymer was used together to control drug delivery speed. To obtain a supercritical nanostructure with a particle size of less than 100 nm, and a particle size of 100 nm or less through changes in temperature and pressure, which are operating variables of the supercritical fluid process, or changes in flow rates of solutions of triclosan and organic solvents and supercritical carbon dioxide. It was possible to set specific process conditions to obtain. |
priorityDate | 2007-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.