| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f0e688f4f0f360c3093469970677fdbe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e0aae33d98e2d787958f0e63e76212a5 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2200-308 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-66
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-175
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 |
| filingDate |
2007-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6a0a8b694a758d4a1271af28bf0bc72
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9701ffc4042e8b29bd8e3969efbbbe9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8a6ebf1c38835451013e5489668fe88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e7a65245462aaf0a4ec5692e105d55f8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5983675ec4a088700c777fa5aad5a7b3 |
| publicationDate |
2009-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20090064891-A |
| titleOfInvention |
Inhibitor of colorectal cancer metastasis, including gene carrier containing gamma-aminobutyric acid A receptor, alpha 1 gene |
| abstract |
The present invention relates to a therapeutic agent for colorectal cancer using a recombinant vector containing a gene encoding a gamma-aminobutyric acid A receptor, alpha 1 (gamma-aminobutyric acid A receptor, α 1, GABRA1). Inhibition of colorectal cancer cell metastasis by introducing a recombinant vector containing a gamma-aminobutyric acid A receptor, a gene encoding alpha 1, into the colorectal cancer cell in which the promoter region is specifically methylated in the cancer cell and the expression of the gene is significantly reduced. It relates to a colorectal cancer treatment agent.n n n According to the present invention, when a recombinant vector containing the gene encoding the gamma-aminobutyric acid A receptor and alpha 1 is treated to colon cancer cells, the proliferation of colon cancer cells is suppressed, which is useful for treating colon cancer. |
| priorityDate |
2007-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |