abstract |
The present invention relates to a method for producing patient cancer modifying antibodies using a new paradigm of screening. By separating anti-cancer antibodies using cancer cell cytotoxicity as an end point, this method allows the production of anti-cancer antibodies for therapeutic and diagnostic purposes. These antibodies can be used as an aid in identifying and diagnosing cancer and in treating primary tumors and tumor metastasis. These anti-cancer antibodies can be conjugated to toxins, enzymes, radioactive compounds, or hematogenous cells. |