| abstract |
Compound (I) is shown which functions as a potent antagonist of the CCR2 or CCR9 receptor. Animal experiments demonstrate that these compounds are useful for treating inflammation, which is a hallmark disease for CCR2 and CCR9. These compounds are generally aryl sulfonamide derivatives and for the treatment of CCR2-mediated and CCR9-mediated diseases as controls in the test for the identification of CCR2 antagonists and as controls in the test for the identification of CCR9 antagonists. Useful in pharmaceutical compositions and methods.n n n Aryl sulfonamide derivatives |