abstract |
The present invention provides a benzodiazepine composition formulated for intranasal administration, comprising a two-component solvent system comprising a first solvent that is soluble in benzodiazepines and can penetrate nasal mucosal tissue, and a second solvent having a slightly lower solubility of benzodiazepines. It includes. The compositions of the present invention can be used to treat various disorders such as panic attacks, muscle spasms, anxiety and seizures, but are not limited to these diseases. In one aspect, the present invention can be used as a therapeutic agent for multiple seizures, and relates to a rapidly acting nasal administration of clonazepam. |