| abstract |
The present invention relates to a serum-free medium for chondrocyte differentiation and proliferation comprising TGFβ1 (transforming growth factor β1). The present invention is very efficient for producing chondrocytes from synovial membrane cells, and in particular because the present invention does not use serum, various problems with serum-containing media such as physiological variability, shelf life, cell specificity, infection, cost And a variety of problems, such as the effect of growth inhibitory agents, and is particularly advantageous in obtaining permission for cell therapy. |