http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20090034805-A

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inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_10420bae4a385935d6b1175c0bee660e
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publicationDate 2009-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20090034805-A
titleOfInvention Method for producing radioactive fluorine labeled organic compound
abstract In the production of [ 18 F] FACBC, a production method capable of reducing the amount of impurities produced is provided.n n n Formula (1):n n n n n n n n Wherein R 1 is a straight or branched chain alkyl group having 1 to 10 carbon atoms or an aromatic substituent, R 2 is a protecting group, and is maintained in a reverse phase column to charge the column with an alkaline solution to remove the compound. By esterification and then withdrawing the alkaline solution from the column:n n n n n n n n A deesterification process for obtaining a compound represented by the formula (X is sodium or potassium)n n n Deprotection of the amino protecting group is carried out to the compound obtained in the deesterification step to give the following formula (3):n n n n n n n n Deprotection process to obtain compound represented byn n n Method for producing a radioactive fluorine-labeled organic compound comprising a.
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Total number of triples: 29.