| abstract |
The present invention is a pharmaceutical oral formulation comprising any form of nicotine for delivery of any form of nicotine to an individual by transmucosal absorption in the oral cavity, wherein the oral formulation is buffered by at least tromethamol. . In addition, methods for oral delivery of nicotine in any form, methods for reducing the urge to smoke or tobacco use, and methods for preparing oral formulations, use of oral formulations for transmucosal absorption of nicotine in the oral cavity of an individual, And the use of nicotine for the preparation of oral formulations for the treatment of tobacco or nicotine dependence, Alzheimer's disease, Crohn's disease, Parkinson's disease, Tourette's syndrome, ulcerative colitis and weight control after smoking cessation. |