http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20090026275-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9fa18e617b8cb55846f831feea60d4bb |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4418 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4409 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4409 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4418 |
| filingDate | 2007-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6fe2e3914054f350f931ec3a30c1df56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4cab201d673df9685006a6be19e5a6b6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8448a040d57c4d40f3f23f00ddcaa1c1 |
| publicationDate | 2009-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20090026275-A |
| titleOfInvention | Compounds and combinations thereof for inhibiting beta-amyloid production, and methods of use thereof |
| abstract | The present invention provides compounds that can be used in combination for the treatment of diseases associated with conditions associated with brain accumulation of Alzheimer's amyloid, such as Alzheimer's disease. In addition, the present invention provides a combination of administering a therapeutically effective amount of a compound that can reduce β-amyloid production and capacitive calcium entry in cells, thereby producing β-amyloid production, β-amyloid deposition, β-associated with brain accumulation of Alzheimer's amyloid. Methods are provided to treat amyloid neurotoxicity (including abnormal hyperphosphorylation of tau) and microglia, or to reduce the risk of expression. The invention also provides a method for diagnosing a disease associated with brain accumulation of Alzheimer's amyloid in an animal or human by administering a diagnostically effective amount of a compound. |
| priorityDate | 2006-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 39.