| abstract |
The present invention provides a coated oral dosage form for delivering any form of nicotine to a subject by rapid intraoral delivery of nicotine, comprising at least one core, any form of nicotine and / or nicotine mimicking agent, At least one coating layer and optionally at least one other additive, wherein the at least one coating layer is buffered, whereby at least tromethamol is used as a buffer. Also contemplated are methods of delivery of nicotine in any form, methods of reducing the urge to smoking or tobacco use, as well as methods of making the coated products and their use for rapid oral absorption of nicotine. |