http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20090023434-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b6171684de68ce62ef3fbf1655618249 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6486 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-534 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
filingDate | 2009-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30df4af05acb075ba54fa31bb34a8fd4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8534c5468d44687d850eaa8f8d3ab84d |
publicationDate | 2009-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20090023434-A |
titleOfInvention | Screening method of anticancer substance or anticancer treatment method using calcein-AM in multilayer cancer cell culture system |
abstract | The present invention relates to a method for screening an anticancer substance or anticancer treatment method using calcein-AM in a multicellular cancer cell (multicellular layer, MCL), specifically, one of the screening systems for the discovery of anticancer candidates effective for solid cancer The anticancer agent was treated by the anticancer candidate substance or candidate anticancer treatment method in the MCL model, followed by successive treatments with calcein-AM (calcein-acetoxymethyl ester), and by measuring the fluorescence intensity distribution of calcein-AM that has passed through the MCL. A method of screening a substance or anticancer treatment method. Using the method of the present invention can know the tissue permeability and anticancer effect of the anticancer candidate, it can be usefully used to search for or evaluate the efficacy of a new anticancer or anticancer therapy for solid cancer. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107367456-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107367456-B |
priorityDate | 2009-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.