abstract |
Selectable estrogen receptor modulators of the general formula (1) and dihydroepiandrosterone, dihydroepiandrosterone sulfate, androst-5-ene-3β, 17β-diol, especially to acceptable warm-blooded animals, including humans And inhibiting and / or osteoporosis, breast cancer, hypercholesterolemia, hyperlipidemia or atherosclerosis, comprising administering any amount of a sex steroid precursor selected from the group consisting of compounds which are converted to one of the precursors in vivo. New methods of medical treatment. In order to inhibit and / or medically treat the development of osteoporosis, administration of bisphosphonates is additionally presented with selective estrogen receptor modulators and / or sex steroid precursors. Also provided herein are pharmacological compositions and kit (s) useful for the delivery of the active ingredient (s).n n n n General formula (1) |