| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1d47ea4a98d4d599e0ff810991424307 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5076
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate |
2007-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_91e174ebaaa6c2b10e91031fe285b87c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_258a4818757c5fcfe2d79c53162676ee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d0c62ad13c7d315bbf9dcd3d1c2578c3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7da05698a39f1709201fa485576fd31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ccca18c6f6fa88b5364bb9cac12a367
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82c139f658f4e77fcaa9862317536a0c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf83296edbf9407dac6b65092a7274ce |
| publicationDate |
2009-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20090016740-A |
| titleOfInvention |
Screening methods for compounds that alter skin and / or hair pigmentation |
| abstract |
The present invention provides a method for identifying compounds that increase or decrease skin and / or hair pigmentation, including determining the ability of a test compound to modulate NCKX (eg NCKX5) -mediated calcium ion migration across the membrane. do. The method comprises exposing a membrane comprising a NCKX molecule or variant, fusion or derivative thereof to a test compound and determining the calcium ion concentration on one or both sides of the membrane directly or indirectly. The invention also relates to kits, nucleic acid molecules, polypeptides and cells useful in the methods of the invention. |
| priorityDate |
2006-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |