http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20080110685-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bbb7c566de48ddc2f6ab493710ddc328 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0071 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 |
filingDate | 2004-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12c71f28d32e9a51f8f85bc41d3e7ca1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a58da8a1f1abcb9ec47ae9328e09980 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26a2040dc1fb55d7d36c86443b9b5647 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df41c9c43fb0067ddd65ef433f1e170a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc61bcc46111b6a63a88b4e5fe5bf257 |
publicationDate | 2008-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20080110685-A |
titleOfInvention | Nonpolar Photoresist Formulation for Photodynamic Therapy |
abstract | The present invention relates to pharmaceutical liposome formulations for photodynamic therapy that are stable even when stored without the need for lyophilization and comprising a nonpolar porphyrin sensitizer and one or more phospholipids. Liposomal formulations provide a therapeutically effective amount of a photosensitizer for intravenous administration. Phospholipids can be modified by PEGylation, ie including polyethylene glycol as an integral part of the phospholipid. The liposomes formed include intracellular nonpolar photosensitizers and are useful for targeting where the nonpolar photosensitizer and the second polar material are used together. When the formulation includes the presence of monosaccharides or polyalcohols, it can be efficiently lyophilized to maintain the size of the liposome vehicle and the therapeutically effective amount of the photosensitizer content. The invention also relates to liposome compositions formed by reconstitution with an aqueous vehicle. The lyophilized formulation, reconstituted with a suitable aqueous vehicle, may also form liposomes useful for intravenous administration. |
priorityDate | 2003-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 95.