| abstract |
The present invention relates to compounds of formula (I) useful as PPAR agonists. Without limitation, diabetes, nephropathy, neuropathy, retinopathy, polycystic ovary syndrome, hypertension, ischemia, seizures, irritable bowel disorders, inflammation, cataracts, cardiovascular disease, metabolic X syndrome, hyper-LDL-cholesterolemia, dyslipidemia One or more symptoms, including hypertriglyceridemia, hypercholesterolemia, mixed hyperlipidemia and hyper-LDL-cholesterolemia, atherosclerosis, obesity and other diseases associated with lipid metabolism and its energy homeostasis problems, the present invention Also described are pharmaceutical compositions and methods for treating with the compounds of. |