http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20080098627-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_30f88fce90a96087c564b89062ebe51d |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0056 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5073 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5084 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2077 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-22 |
| filingDate | 2007-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95d5fe2fc7feb71043b0f622b22af05a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8982535c0568a047e8426b6f20f3bec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf5ec206f2c794c8d564380eeaa066f4 |
| publicationDate | 2008-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20080098627-A |
| titleOfInvention | Drug delivery system comprising a weakly basic selective serotonin 5-HTH3 blocker and an organic acid |
| abstract | The present invention provides a weakly basic, nitrogen-containing selective serotonin 5-HT 3 having a pKa of about 5 to 14 and a solubility of at most about 200 μg / mL at a pH of 6.8 in a sustained release manner to suit a single daily dosing regimen. Formulations, such as capsules, conventional or orally disintegrating tablets that can deliver a blocker into the body, include at least one organic acid that dissolves the weakly basic selective serotonin 5-HT 3 blocker before release into a hostile intestinal environment and the weakly basic drug. Is substantially insoluble. The unit dosage form consists of a plurality of multi-coated particles (ie, immediate-release beads, sustained-release beads and / or one or more delayed, pulsating-release beads populations) and the weak basic blocker and the organic acid are in situ in the acid addition compound. It is not in close contact during processing and / or storage for formation and ensures that the acid is not depleted before drug release is terminated.n n n n Drug delivery system, weak basic drug, organic acid |
| priorityDate | 2006-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 106.