| abstract |
The present invention provides 4,5-dihydro- (1H) -pyrazole (pyrazoline) derivatives as cannabinoid CB1 receptor modulators, pharmaceutical compositions comprising such compounds, methods of preparing such compounds, and novel novel useful for their synthesis. A method for producing an intermediate and a method for preparing a composition. The present invention also provides the use of the compounds and compositions, in particular the use of such compounds or compositions, in which the administration to them is achieved so as to obtain a therapeutic effect on the disorder to which the CB1 receptor is associated or can be treated through manipulation of such receptors. It is about. The compound has formula (I).n n n Formula In n n n n n n n In Formula I,n n n Substituents have the meanings described in the specification.n n n Cannabinoid CB1 receptor modulator, 4,5-dihydro- (1H) -pyrazole derivatives, CB1 receptor potency activity |