| abstract |
The present invention relates to the activity of 3,5-substituted piperidine compounds, these compounds for use in the diagnosis and therapeutic treatment of warm-blooded animals, in particular for the treatment of diseases (= disorders) that depend on the activity of renin, The use of a compound of this class in the manufacture of a pharmaceutical formulation for the treatment of dependent diseases, the use of a compound of this class in the treatment of diseases dependent on the activity of renin, a 3,5-substituted piperidine compound Pharmaceutical formulations, and / or methods of treatment comprising administering 3,5-substituted piperidine compounds, methods of preparing 3,5-substituted piperidine compounds, and novel intermediates and partial steps for their synthesis It is about. Preferred compounds, which may exist as salts, have the structure of Formula I 'n n n <Formula I '>n n n n n n n n Wherein R1, R2, T, R3 and R4 are as defined in the specification. |