abstract |
The present invention relates to virus like particles (VLPs) expressing and / or containing seasonal influenza virus proteins, avian influenza virus proteins and / or influenza virus proteins from pandemic viruses. The present invention includes a vector construct comprising the protein, a cell comprising the construct, an agent comprising the VLPs of the invention and a vaccine. The invention also includes methods of administering VLPs to vertebrates and methods of making the same, including methods of inducing substantial immunity against seasonal and avian influenza or at least one symptom thereof. |