| abstract |
The present invention relates to a combination of placental stem cells and stem cells or progenitor cells obtained from a second cell source, wherein the combination of cells is a engraftment rate of transplanted cells as compared to the case of placenta stem cells or stem cells alone from a second cell source. This is high. This cell combination is referred to as the integrated stem cell population. The invention also provides in vitro methods and in vivo methods and transplantation models for the identification and manufacture of integrated stem cell populations. According to the present invention, placental stem cells, for example, cord blood derived stem cells or progenitor cells, fetal or neonatal stem cells or progenitor cells, adult stem cells or progenitor cells, hematopoietic stem cells or progenitor cells, bone marrow derived stem cells or progenitor cells Can be integrated with |