http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20080080655-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_382ccfc2ebebcaee15aa7cda4cee86bc |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61J2200-20 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61J3-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-148 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61J3-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J2-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61J3-06 |
filingDate | 2006-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de96f956be3f4fc2d97c488bd45af70f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_570e9f8e49305b94bfc5c325a6f355e5 |
publicationDate | 2008-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20080080655-A |
titleOfInvention | Sustained release formulation containing a method for producing drug-containing wax matrix particles, an extruder used in the method, and cilostazol |
abstract | It is an object of the present invention to prepare drug-containing wax matrix particles, in particular drug-containing wax matrix particles having an average particle diameter of 1 mm or less, in a convenient manner, without clogging liquid by recrystallization of the molten drug in the process from melting to spraying. To provide a way.n n n Drug-containing wax matrix particles containing drugs and waxes are prepared by the following steps (i) and (ii): (i) The drug and wax, and the temperature of the barrel (1) and die is at least the melting point of the wax Supplying to an extruder set to a temperature, and (ii) in the die portion 3 provided at the tip of the barrel 1 of the extruder while melt kneading the drug and wax in the extruder. A process for shaping the molten kneaded product of the drug and the wax into a particulate form by spraying and discharging the molten kneaded product of the drug and the wax in a temperature atmosphere below the melting point of the wax from a directly mounted spray nozzle (5). |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102418283-B1 |
priorityDate | 2005-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 697.