| abstract |
The present invention relates to a pharmaceutical composition having thixotropy in which isothermal temperature can be continuously transferred to a gel / sol / gel state by changing its viscosity due to a physical force applied from the outside or the like. The thixotropic pharmaceutical composition of the present invention contains an active substance having pharmacological activity, a biocompatible thickener and a hydrophilic thickener having predetermined thixotropy, and the viscosity of the composition is changed relatively quickly and within an appropriate range so as to be administered. It is easy to quantify the drug to be administered, which makes it possible to administer the correct amount of drug to the patient, as well as high patient compliance with the medication, and is easy to manufacture. |