| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3691a5996e5f4a0235203d1134fdf282 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-12 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0652
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0664
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K6-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0654 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-077
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K6-00 |
| filingDate |
2006-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_366bf25549aedaef0c5670f9600528ff
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a6f510832c801c4ce789854ea5e52bd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7470e5ec71259b67d2a45265e0ffbf6 |
| publicationDate |
2008-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20080056280-A |
| titleOfInvention |
Stem cell differentiation method and its use in the treatment of dental condition |
| abstract |
The present invention relates to a method of proliferation and / or differentiation of mammalian cells, wherein the method has PDL characteristics by exposing or co-culturing to periodontal ligament tissue, periodontal ligament protein or factors derived from periodontal ligament tissue, Obtaining cells that meet at least one of the following characteristics:n n n i) exhibits periodontal characteristics as demonstrated by the Von Kossa method, in which calcium phosphate precipitates are stained from brown to black;n n n ii) decreased bone sialoprotein (bone sialoprotein II or BSP) simultaneously with increased osteopontin and osteocalcin,n n n iii) can be implanted for repair and / or regeneration of periodontal tissue,n n n iv) periodontal disease, or periodontitis, called periodontitis, can be repaired by treatment of the gum line towards the tooth,n n n v) Allowed to host without significant immune response or cell rejection. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019039900-A1 |
| priorityDate |
2005-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |