| abstract |
Modified human PP peptides mentioned in the specification (i) [Lys4, Ser30, Gln34] hPP, (ii) [Lys4, Leu17, Thr30, Glu34] hPP, and (iii) [Lys4, Leu17 oxidized Met30, Glu34] hPP (where “oxidized Met” is sulfoxide or sulfone), and any analogues and derivative forms thereof, are Y2 receptor selective agonists with respect to Y1 and Y4 receptors, for example for appetite suppression and therapeutic angiogenesis. useful. |