| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9019c0ce5cb7b82c85e121f6cac86dce |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-54 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5023
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5044
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6854
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-54 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-02 |
| filingDate |
2004-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fcc387e55b87fd4a1d963e9effbac442
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb08acdd40b61ad66a37003047d40e87
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e7a54a6c00a15f7ca993a5dd9b559dc |
| publicationDate |
2008-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20080049851-A |
| titleOfInvention |
Screening method of inhibitor using the induction of interleukin 18 production by keratinocytes, method of inducing atopic dermatitis-like symptoms, and its use |
| abstract |
Various methods that can be suitably used for elucidating the mechanism of development of atopic dermatitis (AD) or the like and developing therapeutic drugs by using the induction of production of interleukin 18 (IL-18) from keratinocytes (KC) And how to use it. For example, high levels of serum in AD-like lesions can be obtained by applying Staphylococcus aureus protein A (SpA) to the skin of a mouse or by implanting a skin fragment having an AD-like inflammatory skin lesion in a mouse or the like. IgE expression can be reproduced. Thereby, the inhibitor of IL-18 production | generation induction by KC can be screened, for example. |
| priorityDate |
2003-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |