| abstract |
The invention provides an isolated canine influenza virus of subtype H3N8 comprising HA, wherein the amino acid at SEQ ID NO: 4 or more than 99% identical to SEQ ID NO: 4, wherein the amino acids at positions 94 and 233 have the same amino acid sequence as SEQ ID NO: 4; Compositions comprising attenuated or inactivated virus; Isolated or purified HA, NM, MP, M1, NS1, PA, PB1, and PB2 proteins and fragments thereof and compositions comprising them, or optionally nucleic acids encoding them as part of a vector; And a method for inducing an immune response against a canine influenza virus in an animal, comprising administering the composition mentioned above to the animal. |