abstract |
The present invention provides isolated monoclonal antibodies, particularly human monoclonal antibodies that specifically bind with high affinity to PD-Ll. Also provided are nucleic acid molecules encoding expression antibodies, expression vectors, host cells and methods of expressing antibodies of the disclosure. Also provided are immunoconjugates, bispacific molecules, and pharmaceutical compositions comprising the antibodies of the invention. The present disclosure also provides methods for detecting PD-Ll as well as methods for treating various diseases including cancer and infectious diseases using anti-PD-Ll antibodies. |