abstract |
The present invention relates to an affinity matrix comprising a solid phase and an affinity ligand having a peptide bond linked to the solid phase, wherein the affinity ligand having a peptide bond is selected from the group of the following ligands: .n n n a) a peptide comprising the general formula X 1 X 2 X 3 X 4 , wherein X 1 to X 4 are amino acid residues and at least two of X 1 to X 4 are W, Y or F; b) a peptide comprising the general formula X 5 X 6 X 7 X 8 , wherein X 5 to X 8 are amino acid residues, at least one of X 5 to X 8 is W, and one of X 5 to X 8 Peptides of which E is or D; c) poly-amino acids consisting of amino acid monomers of the group consisting of R, K, E and D and amino acid monomers of the group consisting of Y, F and W, preferably poly-KY, poly-KF, poly-KW, poly- The peptides described in RY, poly-RF, poly-RW, poly-EY, poly-DY, poly-EF, poly-EW, poly-DF and poly-DW, provided that a) and b) are composed of 35 amino acid residues. The poly-amino acid described in c) with the maximum length has a minimum length of 20 amino acid residues. |