http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20080035666-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2d3599fb8f8f479dba95ca9bb504884 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-227 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-47 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-18 |
filingDate | 2006-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a15e757efd4ce78a6efc88f2a67fd3a0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_186f3ff12d2b106c19568335010e0823 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7db4e7d81d0e4797a0bdac593020c0e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d91be58c48de0b1ff167faa4378e8f68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_571d790e60f8c52da323e4d6997ae3f4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_622e2b26049c4235b63c4a1dfdee08b5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_197118308f6077fa5842cc84f13aaf08 |
publicationDate | 2008-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20080035666-A |
titleOfInvention | Quinoline derivatives as antimicrobials |
abstract | Use of a compound of formula (I), a pharmaceutically acceptable acid or base addition salt, quaternary amine, stereochemical isomer, tautomer or N-oxide form, for the manufacture of a medicament for the treatment of bacterial infections except mycobacterial infection Is initiated:n n n n n n n n Wheren n n R 1 is hydrogen, halo, haloalkyl, cyano, hydroxy, Ar, Het, alkyl, alkyloxy, alkylthio, alkyloxyalkyl, alkylthioalkyl, Ar-alkyl or di (Ar) alkyl;n n n p is an integer from 1 to 3;n n n s is an integer from 0 to 4;n n n R 2 is hydrogen; Halo; Alkyl; Hydroxy; Mercapto; Optionally substituted alkyloxy; Alkyloxyalkyloxy; Alkylthio; Mono or di (alkyl) amino, wherein alkyl may be optionally substituted; Ar; Het or expression Is a radical of;n n n R 3 is alkyl, Ar, Ar-alkyl, Het or Het-alkyl;n n n q is an integer from 0 to 4;n n n R 4 and R 5 are each independently hydrogen, alkyl or benzyl;n n n R 4 and R 5 may be bonded together, including the N to which they are attached;n n n R 6 is hydrogen, halo, haloalkyl, hydroxy, Ar, alkyl, alkyloxy, alkylthio, alkyloxyalkyl, alkylthioalkyl, Ar-alkyl or di (Ar) alkyl;n n n Two adjacent R 6 radicals together may form naphthyl with the phenyl ring to which they are attached;n n n r is an integer from 1 to 5;n n n R 7 is hydrogen, alkyl, Ar or Het;n n n R 8 is hydrogen, alkyl, hydroxyl, aminocarbonyl, mono or di (alkyl) aminocarbonyl, Ar, Het, alkyl substituted by 1 or 2 Het, or alkyl substituted by 1 or 2 Ar , Het-C (= 0)-or Ar-C (= 0)-;n n n Provided that R 3 is located at position 3 of the quinoline moiety;n n n R 7 is located at position 4 of the quinoline moiety;n n n R 2 is located at position 2 of the quinoline moiety and is hydrogen, hydroxy, mercapto, alkyloxy, alkyloxyalkyloxy, alkylthio, mono or di (alkyl) amino or a formula When it is a radical of;n n n s is 1 to 4. |
priorityDate | 2005-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.