abstract |
New compounds that interact with histamine H3 receptors are defined. Such compounds are particularly useful in the treatment of various diseases or disorders for which histamine H3 interaction is beneficial. Thus, the compounds may find use, for example, in the treatment of diseases of the central nervous system, peripheral nervous system, cardiovascular system, pulmonary emphysema, gastrointestinal system and endocrine system. The novel compound has a core consisting of a six-membered aromatic ring containing at least one nitrogen and two carbon atoms in the ring, with carbon or nitrogen atoms at the remaining positions in the ring. |