| abstract |
The present invention provides a process for the synthesis of heterocyclic compounds such as benzimidazole carboxylic acid core structures having the general formula (Ia-1) and their synthetic intermediates. The compounds of formula la-1 and their synthetic intermediates can be used to prepare heterocyclic derivatives, such as benzimidazole derivatives.n n n <Formula Ia-1>n n n n n n n n Wherein Z, X 1 , X 2 , X 5 , R 2 and R 10 are as defined herein. |