| abstract |
The present invention relates to the prevention, promotion or treatment of infection by immunogenic compositions, vaccines or pharmaceutical compositions, in particular Mycobacterium tuberculosis complex (mycobacterium tuberculosis, Mycobacterium tuberculosis, M africanium, M microti). The immunogenic composition, vaccine or pharmaceutical composition comprises a fusion polypeptide, in particular one or more starvation inducing antigens from Mycobacterium tuberculosis, and the unit of the fusion polypeptide comprises Mycobacterium tuberculosis antigens. Furthermore, the outbreak relates to the use of a vaccine comprising a fusion polypeptide sequence or a nucleic acid sequence of the invention. The immunogenic composition, vaccine or pharmaceutical composition is administered simultaneously with BCG, in admixture with BCG or elsewhere in different sites or routes. |