Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d249a4698cb89e3eb811d2f47114b5e4 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-135 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56983 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6857 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-1027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
filingDate |
2006-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b108bd9af849e2b24382ab6037850023 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6f9cafcaea187d9d502fe804ff961dd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba301d357f9400653067198f7f77bbe7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e979b2b76b4037cdc899efb8696d42a3 |
publicationDate |
2008-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-20080025174-A |
titleOfInvention |
Antibody Preparations with Optimized Aggregation and Fragmentation Profiles |
abstract |
The present invention provides a method for optimizing the production and purification of an antibody formulation suitable for immunospecific binding to an antigen of interest and for parenteral administration to a subject, wherein the formulation is an antibody component upon prolonged storage. Stability is increased due to the decomposition and reduction of aggregation. Such methods are produced by less optimized methods, including less stringent or more readily available transport / storage conditions, less frequent or smaller doses in therapeutic, prophylactic, and diagnostic use of the formulation. Provided are formulations that provide a number of advantages over formulations. The invention further provides methods of using the formulations of the invention. |
priorityDate |
2005-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |