abstract |
The present invention relates to compositions and methods for the treatment of Staphylococcus aureus ( S. aureus ) infections. In particular, the present invention relates to pantone-valentin leucosidine (Panton- S. aureus infections, including vaccines comprising Valentine Leukocidin (PVL) antigens, antibodies binding to PVL antigens, and compositions containing the same, methods of making the compositions, and cases of community-acquired methicillin-resistant infections. The present invention also provides PVL antibodies, eg PVL antibodies specific to a single PVL subunit, and PVL antigens, such as conjugated and mutated PVL antigens. |