Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24e76490bed88751680a5fef9bc73892 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-429 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-424 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-424 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-429 |
filingDate |
2006-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0b9509efe4a4c35528ac9fbb5a339e3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_198a34864813377b660eefb82cf18f70 |
publicationDate |
2008-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-20080016676-A |
titleOfInvention |
Bicyclic 6-alkylidene-penems, a group D beta-lactamase inhibitor |
abstract |
The present invention relates to any bicyclic 6-alkylidene penem which acts as an inhibitor of group D enzyme. β-lactamase hydrolyzes β-lactam antibiotics, a major cause of resistance to bacteria. Compounds of the present invention, when combined with β-lactam antibiotics, will effectively treat living organisms threatened by bacterial infection. According to the present invention there is provided a compound of formula (I) or a pharmaceutically acceptable salt thereof or a hydrolyzable ester R 5 in vivo, and a preferred compound of formula (I).n n n [Formula I]n n n n n n n n [In the above meal,n n n If one of A and B is hydrogen, the other represents an optionally substituted fused bicyclic heteroaryl group; X is O or S] |
priorityDate |
2005-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |