Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e5ad8562c578b061df7a2c3aee9d0e24 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4719 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-533 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-533 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate |
2006-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b92265d611443228079023b02cdeb1fe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dac11ad3e4af560dbe3f2ad92d47d8aa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9e25d2307a48e817d5476f5aeeac5cc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_425db831f7178ec03fcc07a730619ff0 |
publicationDate |
2008-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-20080004994-A |
titleOfInvention |
High-efficiency Screening of 5-Ht6 Receptor Ligand Using Fluorescence Imaging |
abstract |
The present invention relates to a high-efficiency screening method for 5-HT 6 receptor ligands using fluorescence imaging, and more particularly, to a disadvantage of the 5-HT 6 receptor ligand screening method of conventional radioisotope method or fluorescence imaging method without reproducibility. bonded to the 5-HT 6 receptor ligands efficient search method (high-throughput screening, HTS) and, 5-HT 6 receptor using the YTH (yeast two-hybrid) search method overcome by using a fluorescence imaging method in 96-well plates form It is related to the use of HTS that Fyn protein through the discovery of Fyn protein increases the function of 5-HT 6 receptor. Therefore, the present invention is useful for the prevention and treatment of brain diseases associated with depression, cognitive function, Alzheimer's disease and the like. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108926565-A |
priorityDate |
2006-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |