| abstract |
In particular, the present invention relates to compounds wherein W is a methyl (E) -2- (3-methoxy) acrylate group C (CO 2 CH 3 ) = CHOCH 3 or a methyl 2- (3,3-dimethoxy) propanoate group C A process for the preparation of a compound of formula (I) wherein (CO 2 CH 3 ) CH (OCH 3 ) 2 , or a mixture of the two groups, is provided: 1,4-diazabicyclo [2.2.2] Reacting a compound of formula (II) with 2-cyanophenol or a salt thereof in the presence of 0.1 to 2 mol% of octane, or (b) 0.1 to 1,4-diazabicyclo [2.2.2] octane Reacting the compound of formula (III) with the compound of formula (IV) in the presence of 2 mol%. Moreover, this invention relates to the novel precursor of the compound of following formula (I), and its manufacturing method. |