| abstract |
The present invention comprises a heavy chain variable domain, wherein the heavy chain variable region comprises at least 75% identity (homology) to the amino acid sequence set forth in at least one of SEQ ID NOs: 1, 2 or 3 An isolated antibody or fragment, variant or derivative thereof capable of specifically binding to Her2 / neu, characterized by comprising a sequence having or a functional fragment thereof ), And nucleic acid sequences encoding the same, and methods for the production thereof. The invention also includes administering to the patient in need of treatment of Her2 / neu expressing cancer any of the disclosed antibodies, polypeptides or nucleic acid molecules in a therapeutically effective amount. There is also provided a method of treating Her2 / neu that expresses cancer. |