Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_700ff9a01db2075489cb7ed87392dc28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_41a639aa11b9b2f8063a3e6b8b22b557 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-755 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-775 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-775 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
filingDate |
2005-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_624da27805cbf5f3b12060aed8d5c9e0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1a77d50636b1d364378e56ba424015a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9815db43466947ee1dfc3862fc34e10a |
publicationDate |
2007-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-20070092754-A |
titleOfInvention |
Polymers-von Willebrand Factor-Conjugates |
abstract |
The present invention relates to proteinaceous constructs (also termed polymer-VWF-conjugates) comprising plasma and / or recombinant von Willebrand factor (VWF) bound to at least one physiologically acceptable polymer molecule, as well as It relates to a complex of said proteinaceous construct and at least one Factor VIII (FVIII) protein. Physiologically acceptable polymer molecules can be, for example, polyethylene glycol (PEG) or polysialic acid (PSA). The invention also relates to a method for extending the in vivo half-life of VWF or FVIII in the blood of a mammal having a hemorrhagic disease associated with a functional defect or defect of at least one FVIII or VWF. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20140090703-A |
priorityDate |
2004-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |