Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2d3599fb8f8f479dba95ca9bb504884 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-53 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
filingDate |
2005-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4119cece807553a8fd2eda565b4d48cd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_693e04e61fee61f6416f4d2c97fdfe5c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4c01519bbf912730bf595729d511f2c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d5474cddef17d38889696032a37932c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36a77d99e3f2d352355b20fef31812b7 |
publicationDate |
2007-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-20070086003-A |
titleOfInvention |
Protein-coupled receptors |
abstract |
The present invention relates to compounds that modify or modulate the functional properties of G protein coupled receptor GPR39 and GPR39 protein activity. In particular, the present invention relates to methods of screening for agonists or antagonists of GPR39 for identifying agonists or antagonists that regulate gastrointestinal motility and the therapeutic use of such compounds. In another embodiment, the present invention relates to the involvement of GPR39 in metabolic homeostasis, in particular cholesterol levels observed in GPR39 knockout mice. The invention also relates to transgenic animals having mutations in the GPR39 gene. |
priorityDate |
2004-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |