abstract |
A method for treating a disc in which the nucleus pulposus leaks through one or more defects of the annulus. The method includes injecting fibrin sealant into the disc to reduce at least some of the at least one defect, wherein the fibrin sealant injected into the disc comprises fibrinogen and an activating compound, wherein at least some fibrin is formed after injection Wherein the fibrinogen, the activating compound or both are reconstituted with a solution containing at least one additive, provided that the corticosteroid is not present in the fibrin sealant injected into the disc. |