| abstract |
The present invention provides a peptide having a transmembrane protein domain function, a cell transmembrane transporter using the peptide having a transmembrane protein domain function as an active ingredient, a cell membrane permeation complex formed by binding a target substance to the peptide having a transmembrane protein domain function, A transfection kit comprising the peptide having the transmembrane protein domain function and the target substance, the use of the peptide having the transmembrane protein domain function for the production of a cell membrane permeation complex, the cell membrane permeation complex for the manufacture of a medicament And a method of delivering a target substance to a cell, the method comprising administering the cell membrane permeation complex to a subject and introducing the same into a cell.n n n Since the peptide having the function of the transmembrane protein domain of the present invention has excellent cell membrane permeation efficiency than the conventional TAT-derived peptide, it can be used not only for various research fields in cells but also for the treatment of specific diseases to which drugs should be delivered with high efficiency. . Therefore, the peptide having the membrane-permeable protein domain function of the present invention, the cell membrane permeation complex formed by binding a target substance to the peptide, and a method of transporting the target substance using the same to cells can be very useful as a drug delivery system. |