| abstract |
The invention nogak tree (Stewartia koreana) extract, and relates to their use, more particularly to, water, C 1 -4 lower alcohol, a polar solvent, a nonpolar solvent and nogak tree extract extracted with an extraction solvent selected from a mixed solvent thereof And it relates to a pharmaceutical composition for promoting angiogenesis or promoting tissue regeneration containing the same as an active ingredient and cosmetics for wrinkle improvement.n n n The bark tree extract of the present invention promotes the migration and proliferation of vascular endothelial cells and shows excellent effects on angiogenesis and wound recovery, recovery of wounds and frostbite, recovery of surgical sites after surgery, gastric ulcer, ischemic heart disease and hair loss, etc. It is useful for the treatment or prevention of diseases in which angiogenesis is required for treatment and prevention. In addition, the extract of the present invention is useful as a cosmetic for improving wrinkles because it shows skin tissue regeneration effect. |