| abstract |
The present invention relates to a specific reaction DNA chip against the human intestinal flora, and a method for evaluating the human risk by the change in the human intestinal flora.n n n 90 genes that respond significantly to changes in the normal intestinal bacterial flora in colonic crypt cells of mouse intestinal colony-expressing mice were identified, selected, and amplified using LCM (laser captured microdissection), PCR, and microarray techniques. , Purified to prepare a specific reaction DNA chip in the human intestinal flora, and by collecting and amplifying the RNA from colon crypt cells to examine the expression level of the gene, the biological function caused by changes in the normal flora in the human intestine Anomalies can be evaluated directly, simply and sensitively. |