abstract |
A compound of formula (I) wherein n is 1, 2 or 3; R 1 and R 2 are independently selected from hydrogen and alkyl; R 3 is alkyl; R 4 to R 7 are hydrogen, halogen, hydroxy, alkyl, aryl, alkoxy, aryloxy, alkylthio, arylthio, alkylsuloxyl, alkylsulfonyl, arylsuloxy, arylsulfonyl, amino, monoalkylamino, Independently selected from dialkylamino, nitro, cyano, carboxaldehyde, alkylcarbonyl, arylcarbonyl, aminocarbonyl, monoalkylaminocarbonylamino and dialkylaminocarbonylamine; Or R 5 and R 6 together form a carbocyclic or heterocyclic ring: and its pharmaceutically suitable salts and prodrugs, and treatment, in particular of central nervous system diseases and sleep apnea Use of these compounds in the treatment and especially the treatment of obesity. |