http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20070060721-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f0e688f4f0f360c3093469970677fdbe |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10032 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-34 |
| filingDate | 2005-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9fa0c68851393b45e44a3a3837427dc3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07ef506c43a678b268f0b639846aa534 |
| publicationDate | 2007-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20070060721-A |
| titleOfInvention | Recombinant adenovirus comprising DNA sequence encoding EGF-like domain peptide of hiregulin beta 1 and pharmaceutical composition for neuronal differentiation and regeneration comprising the same |
| abstract | The present invention relates to a recombinant adenovirus comprising a DNA sequence encoding an EGF-like domain peptide of HRG (hyregulin) beta1 and a pharmaceutical composition for neuronal differentiation and regeneration comprising the same. Deficient recombinant adenovirus comprising DNA sequences encoding EGF-like domain peptides or analogs of HRG beta1 and migration and differentiation of neurons comprising said recombinant adenovirus, neurite outgrowth, regeneration or neuronal damage, nerve A pharmaceutical composition for the treatment of a disease is provided.n n n Recombinant adenovirus according to the present invention secretes the EGF-like domain peptide of HRG beta 1 to promote the survival and differentiation of neural stem cells, thereby promoting neurite growth and neuronal regeneration. Therefore, the recombinant adenovirus of the present invention and the composition comprising the same are effective in the treatment of various kinds of degenerative neurological diseases or neuroinjury diseases, in particular, prevention of dementia, Parkinson's disease, Alzheimer's disease, epilepsy, stroke, peripheral nerve damage and the like. It is very useful for treatment and treatment with gene therapy. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9034826-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20150079478-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011021916-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011049346-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008040260-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8642552-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101229819-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20190041897-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011021916-A2 |
| priorityDate | 2005-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 456.