| abstract |
Compounds represented by the following formula (I) used for the prophylactic and / or therapeutic treatment of diseases caused by tau protein kinase 1 hyperactivity, such as degenerative neurological diseases (eg, Alzheimer's disease), optically active isomers thereof Or pharmaceutically acceptable salts thereof:n n n n n n n n [Wherein, R 1 represents C 1 -C 12 alkyl; R 2 represents a hydrogen atom or the like; R 3 represents halogen or the like; q represents an integer of 1 to 7; R 4 represents halogen or the like; p represents 0 or an integer from 1 to 5; R 5 represents C 6 -C 10 aryl, heterocycle, or the like; X represents oxygen, NH, or the like]. |