| abstract |
The present invention provides a 4-amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compound of formula (I); Pharmaceutical compositions containing this compound; And low levels of HDL cholesterol and / or high concentrations of LDL-cholesterol and / or high concentrations of certain plasma lipids, including high density lipoprotein (HDL) -cholesterol and lowering certain other plasma lipid concentrations, such as low density lipoprotein (LDL) -cholesterol and triglycerides. It relates to the use of such compounds for the treatment of atherosclerosis and cardiovascular diseases in some mammals, including diseases affected by triglycerides, for example humans.n n n Formula I |